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导师介绍
王印虎
作者: 发布日期:2022-03-20



硕士生导师简历

基本信息                                      

姓名: 王印虎

职称: 讲师

学历: 博士

电话:18954545955

电子信箱:wangyinhuabc@126.com

出生年月:1988.07

研究方向: 抗菌药物研究

毕业学校: 山东大学

务:  

  1. 研究工作简介

基于靶点(例如,AcrB和抗菌肽模拟物等)的抗耐药菌小分子化合物的设计、合成、抗菌活性和抗耐药机理研究。

  1. 发表论文(按时间倒序排列)

(1) Yinhu Wang#, Rawaf Alenazy#, Xinjie Gu, Steven W Polyak, Panpan Zhang, Matthew J Sykes, Na Zhang, Henrietta Venter*, Shutao Ma*. Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance. European Journal of Medicinal Chemistry, 2021, 213, 113049.

(2) Yinhu Wang#, Rawaf Alenzy#, Di Song, Xingbang Liu, Yuetai Teng, Rumana Mowla, Yingang Ma, Steven W. Polyak, Henrietta Venter*, Shutao Ma*. Structural optimization of natural product nordihydroguaretic acid to discover novel analogues as AcrB inhibitors. European Journal of Medicinal Chemistry, 2020, 186, 15, 111910.

(3) Yinhu Wang# **, Chen Qu#, Tingting Liu, Chunhui Wang*. PFKFB3 inhibitors as potential anticancer agents: Mechanisms of action, current developments, and structure-activity relationships. European Journal of Medicinal Chemistry, 2020, 203, 112612.

(4) Yinhu Wang#, Rumana Mowla#, Liwei Guo, Miguel A. De Barros Lopes, Chaobin Jin, Di Song, Shutao Ma* & Henrietta Venter*. Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors. European Journal of Medicinal Chemistry, 2018, 43, 1: 699-709.

(5) Yinhu Wang, Chao Cong, Wern Chern Chai, Ruiqian Dong, Li Jia, Di Song, Ziteng Zhou, Shutao Ma*. Synthesis and antibacterial activity of novel 4"-O-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs. Bioorganic & Medicinal Chemistry Letters, 2017, 27: 3872–3877.

(6) Yinhu Wang#, Rumana Mowla#, Liwei Guo, Abiodun D. Ogunniyi, Taufiq Rahman, Miguel A. De Barros Lopes, Shutao Ma*, Henrietta Venter*. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4: 733-739.

(7) Yinhu Wang, Henrietta Venter, Shutao Ma*. Efflux Pump Inhibitors: A Novel Approach to Combat Efflux-Mediated Drug Resistance in Bacteria. Current Drug Targets, 2016, 17, 6: 702-719.

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